Biliverdin Reductase Protein (full length)
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- Target See all Biliverdin Reductase (BLVRA) Proteins
- Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))
- Protein Type
- Native
- Protein Characteristics
- full length
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Origin
- Rat
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Source
- Rat
- Application
- SDS-PAGE (SDS), Western Blotting (WB)
- Sequence
- MDAEPKRKFG VVVVGVGRAG SVRLRDLKDP RSAAFLNLIG FVSRRELGSL DEVRQISLED ALRSQEIDVA YICSESSSHE DYIRQFLQAG KHVLVEYPMT LSFAAAQELW ELAAQKGRVL HEEHVELLME EFEFLRREVL GKELLKGSLR FTASPLEEER FGFPAFSGIS RLTWLVSLFG ELSLISATLE ERKEDQYMKM TVQLETQNKG LLSWIEEKGP GLKRNRYVNF QFTSGSLEEV PSVGVNKNIF LKDQDIFVQK LLDQVSAEDL AAEKKRIMHC LGLASDIQKL CHQKK
- Specificity
- ~36 kDa
- Purification
- Ion-exchange Purified
- Purity
- >90% pure using SDSPAGE analysis.
- Top Product
- Discover our top product BLVRA Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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This product has been certified >90% pure using SDSPAGE analysis.
- Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- 10 mM Tris pH 7.5, 0.1 mM EDTA, 0.2 mM DTT, 20 % glycerol
- Storage
- -80 °C
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- Target
- Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))
- Alternative Name
- BVR (BLVRA Products)
- Synonyms
- blvra Protein, MGC69310 Protein, BLVRA Protein, zgc:153046 Protein, BVR Protein, Dmel\\CG9471 Protein, BLVR Protein, BVRA Protein, 0610006A11Rik Protein, 2500001N03Rik Protein, Blvr Protein, biliverdin reductase A Protein, biliverdin reductase A L homeolog Protein, CG9471 gene product from transcript CG9471-RA Protein, BLVRA Protein, blvra Protein, blvra.L Protein, CG9471 Protein, Blvra Protein
- Background
- Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH 7.0 and NADPH at pH 8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).
- Gene ID
- 116599
- NCBI Accession
- NP_446302
- UniProt
- P46844
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