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Biliverdin Reductase Protein (full length)

BLVRA Origin: Rat Host: Rat Native >90% pure using SDSPAGE analysis. SDS, WB
Catalog No. ABIN5021775
  • Target See all Biliverdin Reductase (BLVRA) Proteins
    Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))
    Protein Type
    Native
    Protein Characteristics
    full length
    Origin
    • 6
    • 2
    Rat
    Source
    • 5
    • 1
    • 1
    • 1
    Rat
    Application
    SDS-PAGE (SDS), Western Blotting (WB)
    Sequence
    MDAEPKRKFG VVVVGVGRAG SVRLRDLKDP RSAAFLNLIG FVSRRELGSL DEVRQISLED ALRSQEIDVA YICSESSSHE DYIRQFLQAG KHVLVEYPMT LSFAAAQELW ELAAQKGRVL HEEHVELLME EFEFLRREVL GKELLKGSLR FTASPLEEER FGFPAFSGIS RLTWLVSLFG ELSLISATLE ERKEDQYMKM TVQLETQNKG LLSWIEEKGP GLKRNRYVNF QFTSGSLEEV PSVGVNKNIF LKDQDIFVQK LLDQVSAEDL AAEKKRIMHC LGLASDIQKL CHQKK
    Specificity
    ~36 kDa
    Purification
    Ion-exchange Purified
    Purity
    >90% pure using SDSPAGE analysis.
    Top Product
    Discover our top product BLVRA Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    This product has been certified >90% pure using SDSPAGE analysis.

    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    10 mM Tris pH 7.5, 0.1 mM EDTA, 0.2 mM DTT, 20 % glycerol
    Storage
    -80 °C
  • Target
    Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))
    Alternative Name
    BVR (BLVRA Products)
    Synonyms
    blvra Protein, MGC69310 Protein, BLVRA Protein, zgc:153046 Protein, BVR Protein, Dmel\\CG9471 Protein, BLVR Protein, BVRA Protein, 0610006A11Rik Protein, 2500001N03Rik Protein, Blvr Protein, biliverdin reductase A Protein, biliverdin reductase A L homeolog Protein, CG9471 gene product from transcript CG9471-RA Protein, BLVRA Protein, blvra Protein, blvra.L Protein, CG9471 Protein, Blvra Protein
    Background
    Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH 7.0 and NADPH at pH 8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).
    Gene ID
    116599
    NCBI Accession
    NP_446302
    UniProt
    P46844
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