FKBP4 Protein (AA 1-459) (His tag,PA tag)
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- Target See all FKBP4 Proteins
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-459
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FKBP4 protein is labelled with His tag,PA tag.
- Application
- Functional Studies (Func)
- Sequence
- AA 1-459
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The predicted N-terminus is Met 1. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FKBP4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- Alternative Name
- FKBP4 (FKBP4 Products)
- Synonyms
- HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein
- Background
- Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
- Molecular Weight
- 55.1 kDa
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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