IGFBP7 Protein (AA 30-282) (His tag)
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- Target See all IGFBP7 Proteins
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-282
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGFBP7 protein is labelled with His tag.
- Sequence
- AA 30-282
- Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IGFBP7 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Alternative Name
- IGFBP-7 (IGFBP7 Products)
- Synonyms
- zgc:85888 Protein, AGM Protein, FSTL2 Protein, IBP-7 Protein, IGFBP-7 Protein, IGFBP-7v Protein, IGFBPRP1 Protein, MAC25 Protein, PSF Protein, RAMSVPS Protein, TAF Protein, Fstl2 Protein, Mac25 Protein, insulin like growth factor binding protein 7 Protein, insulin-like growth factor binding protein 7 Protein, IGFBP7 Protein, igfbp7 Protein, Igfbp7 Protein
- Background
- Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers.
- Molecular Weight
- 27.0 kDa
- NCBI Accession
- NP_001544
- Pathways
- Growth Factor Binding
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