Haptoglobin Protein (HP)
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- Target See all Haptoglobin (HP) Proteins
- Haptoglobin (HP)
- Protein Type
- Native
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Haptoglobin protein
Protein Source: Human plasma - Purity
- > 95 % pure
- Top Product
- Discover our top product HP Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Reconstitution
- Reconstitute with 1.0 mL of PBS, pH 7.4, per 1.0 mg of antigen.
- Buffer
- Supplied as a lyophilised powder.
- Precaution of Use
- Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C.
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- Target
- Haptoglobin (HP)
- Alternative Name
- Haptoglobin (HP Products)
- Synonyms
- HP Protein, wu:fb64e01 Protein, BP Protein, HP2ALPHA2 Protein, HPA1S Protein, HP-1 Protein, HPR Protein, Zonulin Protein, haptoglobin Protein, haptoglobin-like Protein, HP Protein, hp Protein, Hp Protein, LOC479668 Protein, LOC101102413 Protein
- Background
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An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.
Description: Human plasma.
Alternative Names: HP protein, Haptoglobin, HPT protein, beta polypeptide protein, HP2 alpha2 protein, Haptoglobin protein, MGC111141 protein, HPA1S protein, alpha polypeptide protein, Hp2 alpha protein - Molecular Weight
- Hp 1-1: 86 kDa, Hp 2-1: 200 kDa, Hp 2-2: 400 kDa
- Pathways
- Transition Metal Ion Homeostasis
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