SMAD6 Protein (AA 1-496) (GST tag)
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- Target See all SMAD6 Proteins
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-496
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Origin
- Human
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Source
- Wheat germ
- Purification tag / Conjugate
- This SMAD6 protein is labelled with GST tag.
- Application
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- Purpose
- SMAD6 (Human) Recombinant Protein (P01)
- Sequence
- MFRSKRSGLV RRLWRSRVVP DREEGGSGGG GGGDEDGSLG SRAEPAPRAR EGGGCGRSEV RPVAPRRPRD AVGQRGAQGA GRRRRAGGPP RPMSEPGAGA GSSLLDVAEP GGPGWLPESD CETVTCCLFS ERDAAGAPRD ASDPLAGAAL EPAGGGRSRE ARSRLLLLEQ ELKTVTYSLL KRLKERSLDT LLEAVESRGG VPGGCVLVPR ADLRLGGQPA PPQLLLGRLF RWPDLQHAVE LKPLCGCHSF AAAADGPTVC CNPYHFSRLC GPESPPPPYS RLSPRDEYKP LDLSDSTLSY TETEATNSLI TAPGEFSDAS MSPDATKPSH WCSVAYWEHR TRVGRLYAVY DQAVSIFYDL PQGSGFCLGQ LNLEQRSESV RRTRSKIGFG ILLSKEPDGV WAYNRGEHPI FVNSPTLDAP GGRALVVRKV PPGYSIKVFD FERSGLQHAP EPDAADGPYD PNSVRISFAK GWGPCYSRQF ITSCPCWLEI LLNNPR
- Characteristics
- Human SMAD6 full-length ORF (AAH12986.1, 1 a.a. - 496 a.a.) recombinant protein with GST tag at N-terminal.
- Purification
- in vitro wheat germ expression system
- Top Product
- Discover our top product SMAD6 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
- Storage Comment
- Best use within three months from the date of receipt of this protein.
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- Target
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Alternative Name
- SMAD6 (SMAD6 Products)
- Synonyms
- madh6 Protein, madh7 Protein, Xsmad6 Protein, hst17432 Protein, AOVD2 Protein, HsT17432 Protein, MADH6 Protein, MADH7 Protein, Madh6 Protein, b2b390Clo Protein, Smad6-like Protein, smad6 Protein, wu:fb22g05 Protein, SMAD family member 6 Protein, SMAD family member 6a Protein, smad6 Protein, SMAD6 Protein, Smad6 Protein, smad6a Protein
- Background
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Synonyms: HsT17432,MADH6,MADH7
Gene Description: SMAD family member 6
Gene Name: SMAD6
Gene Summary: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene
GenBank: BC012986.2, AAH12986.1 - Molecular Weight
- 80.96 kDa (theoreatical)
- Gene ID
- 4091
- Pathways
- Chromatin Binding
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