Indian Hedgehog Protein (IHH)
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- Target See all Indian Hedgehog (IHH) Proteins
- Indian Hedgehog (IHH)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Sequence
- IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG
- Characteristics
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.
- Purity
- >96 % as determined by SDS-PAGE and HPLC.
- Sterility
- 0.2 μm filtered
- Top Product
- Discover our top product IHH Protein
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Indian Hedgehog (IHH) (AA 29-202) protein (His tag)
IHH Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Indian Hedgehog (IHH) (AA 28-202) protein (His tag)IHH Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Indian Hedgehog (IHH) (AA 203-411) protein (His tag)IHH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM PB, pH 7.4, 150 mM NaCl
- Storage
- -20 °C
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- Target
- Indian Hedgehog (IHH)
- Alternative Name
- IHH (IHH Products)
- Synonyms
- BDA1 Protein, HHG2 Protein, X-hh Protein, Xbhh Protein, bhh Protein, bhh-a Protein, IHH Protein, ehh Protein, zgc:113262 Protein, indian hedgehog Protein, Indian hedgehog Protein, indian hedgehog S homeolog Protein, Indian hedgehog homolog b Protein, IHH Protein, Ihh Protein, ihh.S Protein, ihhb Protein
- Background
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Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
Synonyms: IHH, - Molecular Weight
- 19.8 kDa
- UniProt
- Q14623
- Pathways
- Hedgehog Signaling
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