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Indian Hedgehog Protein (IHH)

IHH Origin: Human Host: Escherichia coli (E. coli) Recombinant >96 % as determined by SDS-PAGE and HPLC. Func Active
Catalog No. ABIN2830462
  • Target See all Indian Hedgehog (IHH) Proteins
    Indian Hedgehog (IHH)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 10
    • 9
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func)
    Sequence
    IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG
    Characteristics
    Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.
    Purity
    >96 % as determined by SDS-PAGE and HPLC.
    Sterility
    0.2 μm filtered
    Top Product
    Discover our top product IHH Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20 mM PB, pH 7.4, 150 mM NaCl
    Storage
    -20 °C
  • Target
    Indian Hedgehog (IHH)
    Alternative Name
    IHH (IHH Products)
    Synonyms
    BDA1 Protein, HHG2 Protein, X-hh Protein, Xbhh Protein, bhh Protein, bhh-a Protein, IHH Protein, ehh Protein, zgc:113262 Protein, indian hedgehog Protein, Indian hedgehog Protein, indian hedgehog S homeolog Protein, Indian hedgehog homolog b Protein, IHH Protein, Ihh Protein, ihh.S Protein, ihhb Protein
    Background
    Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
    Synonyms: IHH,
    Molecular Weight
    19.8 kDa
    UniProt
    Q14623
    Pathways
    Hedgehog Signaling
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