CXCL6 Protein

Catalog No. ABIN2830025

Product Details

Target: CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Sequence: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN

Characteristics: Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/mL.

Purity: >98 % as determined by SDS-PAGE and HPLC.

Sterility: 0.2 μm filtered

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: CXCL6 (Chemokine (C-X-C Motif) Ligand 6 (CXCL6))

Alternative Name: CXCL6 (CXCL6 Products)

Synonyms: CKA-3 Protein, GCP-2 Protein, GCP2 Protein, SCYB6 Protein, Cxcl6 Protein, CXCL5 Protein, C-X-C motif chemokine ligand 6 Protein, chemokine (C-X-C motif) ligand 5 Protein, CXCL6 Protein, Cxcl6 Protein, CXCL5 Protein

Background: Relevance: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}.
Synonyms: Chemokine alpha 3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6,

Molecular Weight: 7.9 kDa

UniProt: P80162