CXCL3 Protein
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- Target See all CXCL3 Proteins
- CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Sequence
- ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN
- Characteristics
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/mL.
- Purity
- >97 % as determined by SDS-PAGE and HPLC.
- Sterility
- 0.2 μm filtered
- Top Product
- Discover our top product CXCL3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
- Alternative Name
- CXCL3 (CXCL3 Products)
- Synonyms
- CXCL3 Protein, CINC-2b Protein, GRO3 Protein, GROg Protein, MIP-2b Protein, MIP2B Protein, SCYB3 Protein, Cinc-2 Protein, Cinc2 Protein, Gm1960 Protein, Dcip1 Protein, C-X-C motif chemokine ligand 3 Protein, chemokine (C-X-C motif) ligand 3 Protein, CXCL3 Protein, Cxcl3 Protein
- Background
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Relevance: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. {ECO:0000250, ECO:0000269|PubMed:10095777}.
Synonyms: GRO-gamma, Growth-regulated protein gamma, GRO-gamma, Macrophage inflammatory protein 2-beta, MIP2-beta - Molecular Weight
- 7.9 kDa
- UniProt
- P19876
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
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