IL1RAP Protein (AA 21-359) (His tag)
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- Target See all IL1RAP Proteins
- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-359
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL1RAP protein is labelled with His tag.
- Sequence
- AA 21-359
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL1RAP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
- Alternative Name
- IL-1 RAcP (IL1RAP Products)
- Synonyms
- IL1RAP Protein, il-1racp Protein, il-racp Protein, il1r3 Protein, C3orf13 Protein, IL-1RAcP Protein, IL1R3 Protein, 6430709H04Rik Protein, AI255955 Protein, AV239853 Protein, IL-1RAcp Protein, Il1racpb Protein, interleukin 1 receptor accessory protein Protein, IL1RAP Protein, il1rap Protein, il-1racp Protein, Il1rap Protein
- Background
- Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
- Molecular Weight
- 40.2 kDa
- UniProt
- Q9NPH3
- Pathways
- NF-kappaB Signaling, Growth Factor Binding
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