KAT2A Protein (His tag)
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- Target See all KAT2A Proteins
- KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Insect cells (Sf21)
- Purification tag / Conjugate
- This KAT2A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human GCN5 is fused to a His-tag.
- Purity
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product KAT2A Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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~200-300ng are required for standard HAT assay.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2 % NP-40, 50 mM imidazole and 10 % glycerol.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - Expiry Date
- 6 months
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- Target
- KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
- Alternative Name
- GCN5 (KAT2A Products)
- Synonyms
- KAT2A Protein, GCN5L2 Protein, GCN5 Protein, PCAF-b Protein, hGCN5 Protein, 1110051E14Rik Protein, AW212720 Protein, Gcn5 Protein, Gcn5l2 Protein, mmGCN5 Protein, K(lysine) acetyltransferase 2A Protein, lysine acetyltransferase 2A Protein, histone acetyltransferase KAT2A Protein, ras-related protein Rab-5C Protein, KAT2A Protein, LOC100176452 Protein, LOC100597293 Protein, Kat2a Protein
- Background
- GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.
- UniProt
- Q92830
- Pathways
- Chromatin Binding, Tube Formation
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