FGF1 Protein (AA 16-155)
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- Target See all FGF1 Proteins
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 16-155
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human FGF-1 (aa 16-155) is untagged.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FGF1 Protein
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Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) (Active) protein (His tag)
FGF1 Origin: Mouse Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 1-155) (Active) protein (His tag,GST tag)FGF1 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (Active) proteinFGF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (Active) proteinFGF1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) protein (His tag)FGF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) protein (His tag)FGF1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) protein (GST tag)FGF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 1-155) protein (GST tag)FGF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. In PBS containing 0.2 mM DTT.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
- Alternative Name
- FGF-1 (FGF1 Products)
- Background
- Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.
- Molecular Weight
- ~16kDa
- UniProt
- P05230
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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