DLL1 Protein (AA 1-545, Extracellular Domain) (Fc Tag)
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- Target See all DLL1 Proteins
- DLL1 (delta-Like 1 (DLL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Extracellular Domain, AA 1-545
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Origin
- Human
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Source
- CHO Cells
- Purification tag / Conjugate
- This DLL1 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Interacts with human Notch1 (as confirmed by flow cytometry).
- Cross-Reactivity
- Human
- Characteristics
- Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product DLL1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Inhibits adipogenesis of 3T3L-1 cells. Induces the Notch target gene HES-1 when coated on a plate at 1μg/ml.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in distilled water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- DLL1 (delta-Like 1 (DLL1))
- Alternative Name
- DLL1 (DLL1 Products)
- Synonyms
- X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
- Background
- DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
- Molecular Weight
- ~100kDa (SDS-PAGE)
- UniProt
- O00548
- Pathways
- Notch Signaling, Stem Cell Maintenance
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