C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 45-209) protein (Fc Tag)
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- Target See all C-Type Lectin Domain Family 6, Member A (CLEC6A) Proteins
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 45-209
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- Fc Tag
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse dectin-2 (aa 45-209) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product CLEC6A Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
- Alternative Name
- Dectin-2 (CLEC6A Products)
- Synonyms
- CLEC4N Protein, CLECSF10 Protein, CLEC6A Protein, C-type lectin domain containing 6A Protein, C-type lectin domain family 6, member A Protein, CLEC6A Protein, Clec6a Protein
- Background
- Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
- Molecular Weight
- ~58kDa (SDS-PAGE)
- UniProt
- Q9JKF4
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