DNAJC2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all DNAJC2 Proteins
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DNAJC2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ZRF1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DNAJC2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
- Alternative Name
- Zrf1 (DNAJC2 Products)
- Synonyms
- zrf1 Protein, ZRF1 Protein, MPHOSPH11 Protein, MPP11 Protein, ZUO1 Protein, AU020218 Protein, MIDA1 Protein, Zrf1 Protein, Zrf2 Protein, zgc:85671 Protein, DnaJ heat shock protein family (Hsp40) member C2 Protein, DnaJ (Hsp40) homolog, subfamily C, member 2 Protein, dnajc2 Protein, DNAJC2 Protein, Dnajc2 Protein
- Background
- This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
- Molecular Weight
- 65.7 kDa
- NCBI Accession
- NP_001123359
- Pathways
- Chromatin Binding
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