VPS72 Protein (Myc-DYKDDDDK Tag)
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- Target See all VPS72 Proteins
- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VPS72 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human VPS72 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VPS72 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
- Alternative Name
- Vps72 (VPS72 Products)
- Synonyms
- CG4621 Protein, Dmel\\CG4621 Protein, dYL-1 Protein, vps72 Protein, MGC82727 Protein, Vps72 Protein, YL-1 Protein, ACYPI009531 Protein, Tcfl1 Protein, CFL1 Protein, Swc2 Protein, TCFL1 Protein, YL1 Protein, si:dkeyp-24a7.1 Protein, CG4621 gene product from transcript CG4621-RB Protein, vacuolar protein sorting 72 homolog L homeolog Protein, potential vacuolar protein sorting protein Protein, vacuolar protein sorting 72 homolog Protein, vacuolar protein sorting-associated protein 72 homolog Protein, vacuolar protein sorting 72 Protein, vacuolar protein sorting 72 homolog S homeolog Protein, vacuolar protein sorting 72 homolog (S. cerevisiae) Protein, YL-1 Protein, vps72.L Protein, VPS72 Protein, Vps72 Protein, vps72.S Protein, vps72 Protein
- Background
- The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
- Molecular Weight
- 40.4 kDa
- NCBI Accession
- NP_005988
- Pathways
- Stem Cell Maintenance
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