VAV3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all VAV3 Proteins
- VAV3 (Vav 3 Oncogene (VAV3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VAV3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human VAV3 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VAV3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- VAV3 (Vav 3 Oncogene (VAV3))
- Alternative Name
- Vav3 (VAV3 Products)
- Synonyms
- RGD1565941 Protein, A530094I06Rik Protein, AA986410 Protein, Idd18.1 Protein, vav guanine nucleotide exchange factor 3 Protein, vav 3 guanine nucleotide exchange factor Protein, vav 3 oncogene Protein, VAV3 Protein, Vav3 Protein
- Background
- This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molecular Weight
- 32.4 kDa
- NCBI Accession
- NP_001073343
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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