Vasopressin Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735185

Product Details

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Vasopressin protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Arg-vasopressin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Alternative Name: Vasopressin-Neurophysin 2-Copeptin (AVP Products)

Synonyms: ADH Protein, ARVP Protein, AVP-NPII Protein, AVRP Protein, VP Protein, 2610201A18Rik Protein, Akr1a4 Protein, Vp Protein, Vsp Protein, DI Protein, Vas Protein, Adh Protein, Adh1a Protein, Adh1c Protein, adh Protein, arvp Protein, avrp Protein, avp-npii Protein, copeptin Protein, vasotocin Protein, arginine vasopressin Protein, aldo-keto reductase family 1, member A1 (aldehyde reductase) Protein, alcohol dehydrogenase 1 (class I) Protein, AVP Protein, Akr1a1 Protein, Avp Protein, Adh1 Protein, avp Protein

Background: This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20.

Molecular Weight: 15.3 kDa

NCBI Accession: NP_000481

Pathways: cAMP Metabolic Process