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VAC14 Protein (Myc-DYKDDDDK Tag)

VAC14 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735160
  • Target See all VAC14 Proteins
    VAC14 (Vac14 Homolog (VAC14))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This VAC14 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human VAC14 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product VAC14 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    VAC14 (Vac14 Homolog (VAC14))
    Alternative Name
    Vac14 (VAC14 Products)
    Synonyms
    ArPIKfyve Protein, TAX1BP2 Protein, TRX Protein, AA959718 Protein, BC032215 Protein, D8Wsu151e Protein, Tax1bp2 Protein, Trx Protein, ingls Protein, Vac14 homolog L homeolog Protein, Vac14, PIKFYVE complex component Protein, Vac14 homolog (S. cerevisiae) Protein, vac14.L Protein, VAC14 Protein, Vac14 Protein
    Background
    The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010]
    Molecular Weight
    87.8 kDa
    NCBI Accession
    NP_060522
    Pathways
    Inositol Metabolic Process
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