TMX3 Protein (Myc-DYKDDDDK Tag)
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- Target See all TMX3 Proteins
- TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMX3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TXNDC10 / TMX3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TMX3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))
- Alternative Name
- Txndc10,tmx3 (TMX3 Products)
- Synonyms
- tmx3 Protein, pdia13 Protein, txndc10 Protein, txndc10a Protein, TXNDC10 Protein, zgc:110025 Protein, txndc10b Protein, DKFZp469P2316 Protein, PDIA13 Protein, 6430411B10Rik Protein, A730024F05Rik Protein, AV259382 Protein, Txndc10 Protein, mKIAA1830 Protein, thioredoxin-related transmembrane protein 3 S homeolog Protein, thioredoxin related transmembrane protein 3 Protein, thioredoxin related transmembrane protein 3a Protein, thioredoxin-related transmembrane protein 3 L homeolog Protein, thioredoxin-related transmembrane protein 3 Protein, tmx3.S Protein, TMX3 Protein, tmx3a Protein, tmx3.L Protein, tmx3 Protein, Tmx3 Protein
- Background
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- 51.7 kDa
- NCBI Accession
- NP_061895
- Pathways
- Cell RedoxHomeostasis
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