Mps1 Protein (TTK) (Myc-DYKDDDDK Tag)
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- Target See all Mps1 (TTK) Proteins
- Mps1 (TTK)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Mps1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TTK protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TTK Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Mps1 (TTK)
- Alternative Name
- Ttk (TTK Products)
- Synonyms
- CT96 Protein, ESK Protein, MPH1 Protein, MPS1 Protein, MPS1L1 Protein, PYT Protein, AL022661 Protein, Esk1 Protein, Mps1 Protein, esk Protein, mps1 Protein, ncp Protein, Ttk protein kinase Protein, TTK protein kinase Protein, ttk protein kinase Protein, Ttk Protein, TTK Protein, ttk Protein
- Background
- This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 96.9 kDa
- NCBI Accession
- NP_003309
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