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Mps1 Protein (TTK) (Myc-DYKDDDDK Tag)

TTK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734513
  • Target See all Mps1 (TTK) Proteins
    Mps1 (TTK)
    Protein Type
    Recombinant
    Origin
    • 5
    • 2
    • 2
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Mps1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TTK protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TTK Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Mps1 (TTK)
    Alternative Name
    Ttk (TTK Products)
    Synonyms
    CT96 Protein, ESK Protein, MPH1 Protein, MPS1 Protein, MPS1L1 Protein, PYT Protein, AL022661 Protein, Esk1 Protein, Mps1 Protein, esk Protein, mps1 Protein, ncp Protein, Ttk protein kinase Protein, TTK protein kinase Protein, ttk protein kinase Protein, Ttk Protein, TTK Protein, ttk Protein
    Background
    This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    96.9 kDa
    NCBI Accession
    NP_003309
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