TSHZ3 Protein (Myc-DYKDDDDK Tag)
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- Target See all TSHZ3 Proteins
- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TSHZ3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TSHZ3 / ZNF537 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TSHZ3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
- Alternative Name
- Tshz3,znf537 (TSHZ3 Products)
- Synonyms
- ZNF537 Protein, A630038G13Rik Protein, Tsh3 Protein, Zfp537 Protein, mKIAA1474 Protein, teashirt3 Protein, TSH3 Protein, teashirt zinc finger homeobox 3 Protein, teashirt zinc finger family member 3 Protein, TSHZ3 Protein, Tshz3 Protein
- Background
- This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients.
- Molecular Weight
- 118.4 kDa
- NCBI Accession
- NP_065907
- Pathways
- Regulation of Muscle Cell Differentiation
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