NTRK3 Protein (DYKDDDDK Tag)
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- Target See all NTRK3 Proteins
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Insect cells (Sf9)
- Purification tag / Conjugate
- This NTRK3 protein is labelled with DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TrkC (C-term DDK tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NTRK3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Alternative Name
- Trkc (NTRK3 Products)
- Synonyms
- TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein
- Background
- This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 44.7 kDa
- NCBI Accession
- NP_001012338
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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