TJP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all TJP2 Proteins
- TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TJP2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TJP2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TJP2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
- Alternative Name
- Tjp2 (TJP2 Products)
- Synonyms
- C9DUPq21.11 Protein, DFNA51 Protein, DUP9q21.11 Protein, X104 Protein, ZO2 Protein, ZO-2 Protein, zo2 Protein, tjp2 Protein, x104 Protein, zo-2 Protein, wu:fb62b09 Protein, zgc:92094 Protein, tight junction protein 2 Protein, tight junction protein 2 L homeolog Protein, tight junction protein 2b (zona occludens 2) Protein, TJP2 Protein, Tjp2 Protein, tjp2.L Protein, tjp2b Protein
- Background
- This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
- Molecular Weight
- 133.8 kDa
- NCBI Accession
- NP_004808
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