TYMS Protein (Myc-DYKDDDDK Tag)
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- Target See all TYMS Proteins
- TYMS (Thymidylate Synthetase (TYMS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TYMS protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Thymidylate synthase (TS) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TYMS Protein
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Thymidylate Synthetase (TYMS) (AA 1-313) protein (His tag)
TYMS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Thymidylate Synthetase (TYMS) (AA 111-210) protein (GST tag)TYMS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Thymidylate Synthetase (TYMS) (AA 1-313) protein (GST tag)TYMS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TYMS (Thymidylate Synthetase (TYMS))
- Alternative Name
- Thymidylate Synthase (Ts) (TYMS Products)
- Synonyms
- FN1 Protein, ECK2823 Protein, JW2795 Protein, ts Protein, Ts Protein, HST422 Protein, TMS Protein, TS Protein, thymidylate synthetase Protein, contains intron in T4 phage Protein, ThyE Protein, thymidylate synthase Protein, thymidylate synthetase L homeolog Protein, TYMS Protein, thyA Protein, td Protein, thyE Protein, DDA3937_RS04960 Protein, tyms.L Protein, XBJ1_RS15770 Protein, EAMY_RS20680 Protein, Tyms Protein
- Target Type
- Viral Protein
- Background
- Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
- Molecular Weight
- 35.5 kDa
- NCBI Accession
- NP_001062
- Pathways
- Mitotic G1-G1/S Phases
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