THG1L Protein (Myc-DYKDDDDK Tag)
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- Target See all THG1L Proteins
- THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This THG1L protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human THG1L / ICF45 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product THG1L Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
- Alternative Name
- Thg1l,icf45 (THG1L Products)
- Synonyms
- ICF45 Protein, IHG-1 Protein, 1700121M19Rik Protein, 5730409G07Rik Protein, AA387658 Protein, tRNA-histidine guanylyltransferase 1 like Protein, tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Protein, tRNA-histidine guanylyltransferase 1-like Protein, THG1L Protein, Thg1l Protein
- Background
- The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 34.7 kDa
- NCBI Accession
- NP_060342
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