TCAP Protein (His tag)
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- Target See all TCAP Proteins
- TCAP (Titin-Cap (Telethonin) (TCAP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TCAP protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Telethonin / TCAP (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TCAP Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TCAP (Titin-Cap (Telethonin) (TCAP))
- Alternative Name
- Telethonin,tcap (TCAP Products)
- Synonyms
- TCAP Protein, CMD1N Protein, LGMD2G Protein, T-cap Protein, TELE Protein, telethonin Protein, AI503981 Protein, AJ223855 Protein, titin-cap Protein, titin-cap (telethonin) Protein, titin-cap S homeolog Protein, TCAP Protein, tcap Protein, tcap.S Protein, Tcap Protein
- Background
- Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
- Molecular Weight
- 18.9 kDa
- NCBI Accession
- NP_003664
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