CCL25 Protein (Transcript Variant 1)

Catalog No. ABIN2733398

Product Details

Target: CCL25 (Chemokine (C-C Motif) Ligand 25 (CCL25))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)

Specificity: Optimal preservation of protein structure, post-translational modifications and functions.

Characteristics:

• Recombinant human TECK / CCL25 (transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Determined by its ability to chemoattrract human monocytes using a concentration range of 1.0-10.0 ng/ml.

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handling Advice: Resuspend the protein in the desired concentration in proper buffer

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CCL25 (Chemokine (C-C Motif) Ligand 25 (CCL25))

Alternative Name: Teck,ccl25 (CCL25 Products)

Synonyms: CCL25 Protein, Ckb15 Protein, SCYA25 Protein, TECK Protein, A130072A22Rik Protein, AI852536 Protein, CKb15 Protein, Scya25 Protein, C-C motif chemokine ligand 25 Protein, C-C motif chemokine 25 Protein, chemokine (C-C motif) ligand 25 Protein, Ccl25 Protein, CCL25 Protein, ccl25 Protein

Background: This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants.

Molecular Weight: 14.2 kDa

NCBI Accession: NP_005615