TCF4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all TCF4 Proteins
- TCF4 (Transcription Factor 4 (TCF4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TCF4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TCF4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TCF4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TCF4 (Transcription Factor 4 (TCF4))
- Alternative Name
- Tcf4 (TCF4 Products)
- Synonyms
- E2-2 Protein, ITF-2 Protein, ITF2 Protein, PTHS Protein, SEF-2 Protein, SEF2 Protein, SEF2-1 Protein, SEF2-1A Protein, SEF2-1B Protein, TCF-4 Protein, bHLHb19 Protein, 5730422P05Rik Protein, ASP-I2 Protein, E2.2 Protein, ITF-2b Protein, ME2 Protein, MITF-2A Protein, MITF-2B Protein, TFE Protein, Tcf-4 Protein, TCF7L2 Protein, XE2 Protein, Xtcf-4 Protein, Xtcf4 Protein, e2-A Protein, tcf-4 Protein, transcription factor 4 Protein, transcription factor 4 S homeolog Protein, TCF4 Protein, Tcf4 Protein, tcf4 Protein, tcf4.S Protein
- Background
- This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to > 50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.
- Molecular Weight
- 71.1 kDa
- NCBI Accession
- NP_003190
- Pathways
- WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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