TBL1X Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all TBL1X Proteins
- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TBL1X protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TBL1 / TBL1X (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TBL1X Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
- Alternative Name
- Tbl1,tbl1x (TBL1X Products)
- Synonyms
- zgc:158242 Protein, TBL1X Protein, 5330429M20 Protein, Tbl1 Protein, RGD1563868 Protein, EBI Protein, SMAP55 Protein, TBL1 Protein, transducin beta like 1X-linked Protein, transducin (beta)-like 1X-linked Protein, F-box-like/WD repeat-containing protein TBL1X Protein, transducin (beta)-like 1 X-linked Protein, TBL1X Protein, tbl1x Protein, LOC100446205 Protein, LOC100470467 Protein, Tbl1x Protein
- Background
- The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
- Molecular Weight
- 62.3 kDa
- NCBI Accession
- NP_005638
- Pathways
- Sensory Perception of Sound, Regulation of Lipid Metabolism by PPARalpha
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