SGSH Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732936

Product Details

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SGSH protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Sulphamidase / SGSH protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Alternative Name: Sulphamidase,sgsh (SGSH Products)

Synonyms: HSS Protein, MPS3A Protein, SFMD Protein, 4632406A19Rik Protein, N-sulfoglucosamine sulfohydrolase Protein, N-sulfoglucosamine sulfohydrolase (sulfamidase) Protein, SGSH Protein, Sgsh Protein

Background: This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

Molecular Weight: 54.6 kDa

NCBI Accession: NP_000190

Pathways: Glycosaminoglycan Metabolic Process