STIP1 Protein (DYKDDDDK Tag)
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- Target See all STIP1 Proteins
- STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Insect cells (Sf9)
- Purification tag / Conjugate
- This STIP1 protein is labelled with DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human STIP1 (full length, C-term DDK tag) protein expressed in sf9 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product STIP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))
- Alternative Name
- Stip1 (STIP1 Products)
- Synonyms
- HOP Protein, IEF-SSP-3521 Protein, P60 Protein, STI1 Protein, STI1L Protein, Hop Protein, Sti1 Protein, p60 Protein, MGC53256 Protein, stip1 Protein, MGC76181 Protein, MGC82554 Protein, zgc:92133 Protein, stress induced phosphoprotein 1 Protein, stress-induced phosphoprotein 1 Protein, stress induced phosphoprotein 1 L homeolog Protein, Stress-induced-phosphoprotein 1 Protein, stress-induced-phosphoprotein 1 Protein, stress induced phosphoprotein 1 S homeolog Protein, STIP1 Protein, Stip1 Protein, stip1.L Protein, GL50803_27310 Protein, PGTG_06468 Protein, stip1 Protein, stip1.S Protein
- Background
- STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A MIM 140550) and HSP90 (see HSP90AA1 MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
- Molecular Weight
- 62.6 kDa
- NCBI Accession
- NP_006810
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