STIP1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732854

Product Details

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This STIP1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human STIP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Alternative Name: Stip1 (STIP1 Products)

Synonyms: HOP Protein, IEF-SSP-3521 Protein, P60 Protein, STI1 Protein, STI1L Protein, Hop Protein, Sti1 Protein, p60 Protein, MGC53256 Protein, stip1 Protein, MGC76181 Protein, MGC82554 Protein, zgc:92133 Protein, stress induced phosphoprotein 1 Protein, stress-induced phosphoprotein 1 Protein, stress induced phosphoprotein 1 L homeolog Protein, Stress-induced-phosphoprotein 1 Protein, stress-induced-phosphoprotein 1 Protein, stress induced phosphoprotein 1 S homeolog Protein, STIP1 Protein, Stip1 Protein, stip1.L Protein, GL50803_27310 Protein, PGTG_06468 Protein, stip1 Protein, stip1.S Protein

Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A MIM 140550) and HSP90 (see HSP90AA1 MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]

Molecular Weight: 62.5 kDa

NCBI Accession: NP_006810