NCOA1 Protein (His tag)
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- Target See all NCOA1 Proteins
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Insect cells (Sf9)
- Purification tag / Conjugate
- This NCOA1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SRC1 (C-term polyhistidine tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NCOA1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
- Alternative Name
- Src1 (NCOA1 Products)
- Synonyms
- F-SRC-1 Protein, KAT13A Protein, RIP160 Protein, SRC1 Protein, bHLHe42 Protein, bHLHe74 Protein, si:dkey-5g7.6 Protein, si:dkey-34f16.6 Protein, NCOA1 Protein, SRC-1 Protein, nuclear receptor coactivator 1 Protein, NCOA1 Protein, ncoa1 Protein, Ncoa1 Protein
- Background
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
- Molecular Weight
- 60 kDa
- NCBI Accession
- NP_005408
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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