SOCS6 Protein (His tag)
-
- Target See all SOCS6 Proteins
- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SOCS6 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human SOCS6 / CIS4 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SOCS6 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the N-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
- Alternative Name
- Socs6,cis4 (SOCS6 Products)
- Synonyms
- CIS-4 Protein, CIS4 Protein, HSPC060 Protein, SOCS-4 Protein, SOCS-6 Protein, SOCS4 Protein, SSI4 Protein, STAI4 Protein, STATI4 Protein, socs6 Protein, MGC81477 Protein, SOCS6 Protein, 1500012M23Rik Protein, 5830401B18Rik Protein, AI447482 Protein, Cis4 Protein, Cish4 Protein, Socs4 Protein, socs6l Protein, zgc:64107 Protein, wu:fb77f06 Protein, suppressor of cytokine signaling 6 Protein, suppressor of cytokine signaling 6 L homeolog Protein, suppressor of cytokine signaling Protein, suppressor of cytokine signaling 6b Protein, SOCS6 Protein, Socs6 Protein, socs6.L Protein, socs6 Protein, socs6b Protein
- Background
- The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
- Molecular Weight
- 59.5
- NCBI Accession
- NP_004223
- Pathways
- JAK-STAT Signaling, Carbohydrate Homeostasis
-