SNAPIN Protein (Myc-DYKDDDDK Tag)
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- Target See all SNAPIN Proteins
- SNAPIN (SNAP-Associated Protein (SNAPIN))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SNAPIN protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SNAPIN protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SNAPIN Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SNAPIN (SNAP-Associated Protein (SNAPIN))
- Alternative Name
- Snapin (SNAPIN Products)
- Synonyms
- SNAPAP Protein, si:dkey-222b8.2 Protein, SNAPIN Protein, BLOC1S7 Protein, BLOS7 Protein, 25kDa Protein, AA407989 Protein, AV026596 Protein, Bloc1s7 Protein, Snap25bp Protein, Snapap Protein, SNAP associated protein Protein, SNAP-associated protein L homeolog Protein, SNAP-associated protein Protein, SNAPIN Protein, snapin.L Protein, snapin Protein, Snapin Protein
- Background
- The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 14.7 kDa
- NCBI Accession
- NP_036569
- Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis
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