SH2B2 Protein (Myc-DYKDDDDK Tag)
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- Target See all SH2B2 Proteins
- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SH2B2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SH2B2 / APS protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SH2B2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
- Alternative Name
- Sh2b2,aps (SH2B2 Products)
- Synonyms
- APS Protein, Aps Protein, SH2B adaptor protein 2 Protein, SH2B2 Protein, Sh2b2 Protein
- Background
- The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt&aposs lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
- Molecular Weight
- 72.1 kDa
- NCBI Accession
- NP_066189
- Pathways
- Carbohydrate Homeostasis, Brown Fat Cell Differentiation
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