SGK1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all SGK1 Proteins
- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SGK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SGK1 / SGK (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SGK1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
- Alternative Name
- Sgk1,sgk (SGK1 Products)
- Synonyms
- SGK Protein, Sgk Protein, sgk-B Protein, sgk2 Protein, cb1083 Protein, sgk Protein, wu:fc20a09 Protein, sgk-A Protein, sgk1 Protein, sgk1-a Protein, sgk1-b Protein, serum/glucocorticoid regulated kinase 1 Protein, Serine/threonine-protein kinase sgk-1 Protein, serum/glucocorticoid regulated kinase 1 S homeolog Protein, serum/glucocorticoid regulated kinase 1 L homeolog Protein, SGK1 Protein, Sgk1 Protein, sgk-1 Protein, sgk1.S Protein, sgk1 Protein, sgk1.L Protein
- Background
- This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
- Molecular Weight
- 48.8 kDa
- NCBI Accession
- NP_005618
- Pathways
- MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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