SF3B3 Protein (Myc-DYKDDDDK Tag)
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- Target See all SF3B3 Proteins
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SF3B3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SF3B3 / SAP130 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SF3B3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Alternative Name
- Sf3b3,sap130 (SF3B3 Products)
- Synonyms
- GB11574 Protein, rse1 Protein, sap130 Protein, sf3b130 Protein, staf130 Protein, sf3b3 Protein, 1810061H24Rik Protein, 5730409A01Rik Protein, AA409318 Protein, D8Ertd633e Protein, RSE1 Protein, SAP130 Protein, mKIAA0017 Protein, ik:tdsubc_2b2 Protein, wu:fb81f05 Protein, xx:tdsubc_2b2 Protein, zgc:55440 Protein, SF3b130 Protein, STAF130 Protein, splicing factor 3b subunit 3 Protein, splicing factor 3B subunit 3 Protein, splicing factor 3b, subunit 3, 130kDa Protein, splicing factor 3b subunit 3 L homeolog Protein, splicing factor 3b, subunit 3 Protein, SF3B3 Protein, LOC550935 Protein, sf3b3 Protein, Sf3b3 Protein, LOC100178056 Protein, sf3b3.L Protein
- Background
- This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
- Molecular Weight
- 135.4 kDa
- NCBI Accession
- NP_036558
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