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SERPINB2 Protein (Transcript Variant 2)

SERPINB2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
Catalog No. ABIN2731773
  • Target See all SERPINB2 Proteins
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 9
    • 4
    • 3
    • 2
    Human
    Source
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human SERPINB2 / PAI2 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37C. Half maximal inhibition against 1.0 ug/mL of single chain tPA was obtained at a concentration of 1.0 ug/mL
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    Discover our top product SERPINB2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handling Advice
    Resuspend the protein in the desired concentration in proper buffer
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    Alternative Name
    Serpinb2,pai2 (SERPINB2 Products)
    Synonyms
    HsT1201 Protein, PAI Protein, PAI-2 Protein, PAI2 Protein, PLANH2 Protein, SERPINB2 Protein, Planh2 Protein, ovalbumin Protein, Pai2a Protein, serpin family B member 2 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 2 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 2 Protein, SERPINB2 Protein, Serpinb2 Protein
    Target Type
    Amino Acid
    Background
    Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    45.6 kDa
    NCBI Accession
    NP_002566
    Pathways
    Autophagy
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