Septin 5 Protein (SEPT5) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731689

Product Details

Target: Septin 5 (SEPT5)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Septin 5 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Septin-5 (SEPT5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Septin 5 (SEPT5)

Alternative Name: Septin-5 (Sept5) (SEPT5 Products)

Synonyms: sept5 Protein, fj37h04 Protein, zgc:73218 Protein, wu:fj37h04 Protein, SEPT5 Protein, Cdcrel-1 Protein, Cdcrel1 Protein, Pnutl1 Protein, 5-Sep Protein, CDCrel-1A Protein, CDCREL Protein, CDCREL-1 Protein, CDCREL1 Protein, H5 Protein, HCDCREL-1 Protein, PNUTL1 Protein, septin 5a Protein, septin 5 Protein, sept5a Protein, SEPT5 Protein, sept5 Protein, Sept5 Protein

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Molecular Weight: 42.6 kDa

NCBI Accession: NP_002679

Pathways: Synaptic Vesicle Exocytosis