Seladin 1 Protein (Myc-DYKDDDDK Tag)
DHCR24
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- Target See all Seladin 1 (DHCR24) Proteins
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Seladin 1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Seladin-1 / DHCR24 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DHCR24 Protein
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24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) protein (GST tag)
DHCR24 Origin: Human Host: Wheat germ Recombinant ELISA, AA, AP, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Alternative Name
- Seladin-1,dhcr24 (DHCR24 Products)
- Synonyms
- MGC82737 Protein, zgc:101638 Protein, DCE Protein, Nbla03646 Protein, SELADIN1 Protein, seladin-1 Protein, 2310076D10Rik Protein, 5830417J06Rik Protein, mKIAA0018 Protein, 24-dehydrocholesterol reductase Protein, 24-dehydrocholesterol reductase S homeolog Protein, delta(24)-sterol reductase Protein, DHCR24 Protein, dhcr24.S Protein, dhcr24 Protein, LOC5575872 Protein, CpipJ_CPIJ000670 Protein, Dhcr24 Protein
- Background
- This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
- Molecular Weight
- 57.6 kDa
- NCBI Accession
- NP_055577
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