RHOA Protein (Myc-DYKDDDDK Tag)
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- Target See all RHOA Proteins
- RHOA (Ras Homolog Gene Family, Member A (RHOA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RHOA protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RhoA protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RHOA Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RHOA (Ras Homolog Gene Family, Member A (RHOA))
- Alternative Name
- Rhoa (RHOA Products)
- Synonyms
- ARH12 Protein, ARHA Protein, RHO12 Protein, RHOH12 Protein, Arha Protein, Arha1 Protein, Arha2 Protein, arha Protein, arha2 Protein, xrhoa Protein, arh12 Protein, rho12 Protein, rhoh12 Protein, rhoa Protein, RHO1 Protein, Rhoa Protein, wu:fa66g04 Protein, wu:fb26g07 Protein, zgc:66058 Protein, zgc:85805 Protein, ARHC Protein, rhoae Protein, zgc:64015 Protein, ras homolog family member A Protein, ras homolog family member A S homeolog Protein, ras homolog family member A L homeolog Protein, ras homolog gene family, member Aa Protein, ras homolog family member Ca Protein, RHOA Protein, Rhoa Protein, rhoa.S Protein, rhoa Protein, rhoa.L Protein, rhoaa Protein, rhoca Protein
- Background
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
- Molecular Weight
- 21.6 kDa
- NCBI Accession
- NP_001655
- Pathways
- Microtubule Dynamics, WNT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
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