Relaxin 2 Protein (RLN2) (Transcript Variant 2)

Catalog No. ABIN2730699

Product Details

Target: Relaxin 2 (RLN2)

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Relaxin 2 / RLN2 (transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handling Advice: Resuspend the protein in the desired concentration in proper buffer

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Relaxin 2 (RLN2)

Alternative Name: Relaxin 2,rln2 (RLN2 Products)

Synonyms: H2 Protein, H2-RLX Protein, RLXH2 Protein, bA12D24.1.1 Protein, bA12D24.1.2 Protein, RFLX Protein, rln2 Protein, rln3c Protein, rlx3c Protein, si:rp71-39b20.5 Protein, relaxin 2 Protein, insulin-like 3 (Leydig cell) Protein, RLN2 Protein, insl3 Protein

Background: This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.

Molecular Weight: 6 kDa

NCBI Accession: NP_005050

Pathways: Hormone Activity