RASGRP2 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- Target See all RASGRP2 Proteins
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 4
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RASGRP2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RASGRP2 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RASGRP2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
- Alternative Name
- Rasgrp2 (RASGRP2 Products)
- Synonyms
- CALDAG-GEFI Protein, CDC25L Protein, xrasgrp2 Protein, RASGRP2 Protein, Caldaggef1 Protein, CalDAG-GEFI Protein, rasgrp2 Protein, RAS guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog Protein, RAS, guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog Protein, RASGRP2 Protein, rasgrp2.S Protein, Rasgrp2 Protein, rasgrp2.L Protein
- Background
- The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.
- Molecular Weight
- 69.1 kDa
- NCBI Accession
- NP_001092141
- Pathways
- TCR Signaling
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