PTPRO Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all PTPRO Proteins
- PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTPRO protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTPRO (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPRO Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))
- Alternative Name
- Ptpro (PTPRO Products)
- Synonyms
- GLEPP1 Protein, RPTP-BK Protein, D28 Protein, PTPBK Protein, PTPROt Protein, PTPU2 Protein, PTPoc Protein, PTPphi Protein, Ptpn15 Protein, R-PTP-O Protein, NPHS6 Protein, PTP-OC Protein, PTP-U2 Protein, PTPROT Protein, protein tyrosine phosphatase, receptor type O Protein, protein tyrosine phosphatase, receptor type, O Protein, PTPRO Protein, Ptpro Protein
- Background
- This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.
- Molecular Weight
- 47 kDa
- NCBI Accession
- NP_109594
- Pathways
- Cell-Cell Junction Organization
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