PRKAA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all PRKAA1 Proteins
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PRKAA1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PRKAA1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKAA1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- Alternative Name
- Prkaa1 (PRKAA1 Products)
- Synonyms
- AMPK Protein, AMPKa1 Protein, cb116 Protein, im:7154392 Protein, sb:cb130 Protein, wu:fa94c10 Protein, AMPK1 Protein, AMPKalpha1 Protein, AI194361 Protein, AI450832 Protein, AL024255 Protein, C130083N04Rik Protein, ampk Protein, ampka1 Protein, PRKAA1 Protein, protein kinase AMP-activated catalytic subunit alpha 1 Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog Protein, PRKAA1 Protein, prkaa1 Protein, Prkaa1 Protein, prkaa1.L Protein
- Background
- The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Molecular Weight
- 63.8 kDa
- NCBI Accession
- NP_006242
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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