PPP2R4 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all PPP2R4 Proteins
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PPP2R4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PPP2R4 / PTPA (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PPP2R4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
- Alternative Name
- Ppp2r4,ptpa (PPP2R4 Products)
- Synonyms
- PP2A Protein, PR53 Protein, PTPA Protein, 2610042B21Rik Protein, C77440 Protein, N28142 Protein, PTPRA Protein, Ppp2r4 Protein, fc23d07 Protein, ppp2r4 Protein, wu:fc23d07 Protein, zgc:92766 Protein, pp2a Protein, ppp2r4.L Protein, pr53 Protein, ptpa Protein, protein phosphatase 2 phosphatase activator Protein, protein phosphatase 2 protein activator Protein, protein phosphatase 2 phosphatase activator L homeolog Protein, PTPA Protein, Ptpa Protein, ptpa Protein, ptpa.L Protein
- Background
- Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B&apos/PR61, and B&apos&apos/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B&apos family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 36.6 kDa
- NCBI Accession
- NP_066954
- Pathways
- PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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