PMM2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729213

Product Details

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PMM2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PMM2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Alternative Name: Pmm2 (PMM2 Products)

Synonyms: cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein

Background: The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Molecular Weight: 27.9 kDa

NCBI Accession: NP_000294