Plakophilin 1 Protein (PKP1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729111

Product Details

Target: Plakophilin 1 (PKP1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Plakophilin 1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Plakophilin 1 / PKP1 (transcript variant 1a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Plakophilin 1 (PKP1)

Alternative Name: Plakophilin 1,pkp1 (PKP1 Products)

Synonyms: PKP1 Protein, fb30d08 Protein, wu:fb30d08 Protein, AI528551 Protein, B6P Protein, plakophilin 1 Protein, plakophilin 1b Protein, PKP1 Protein, pkp1b Protein, Pkp1 Protein

Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 80.3 kDa

NCBI Accession: NP_001005337