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PIM1 Protein (Myc-DYKDDDDK Tag)

PIM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728984
  • Target See all PIM1 Proteins
    PIM1 (Pim-1 Oncogene (PIM1))
    Protein Type
    Recombinant
    Origin
    • 6
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PIM1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PIM1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PIM1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PIM1 (Pim-1 Oncogene (PIM1))
    Alternative Name
    Pim1 (PIM1 Products)
    Synonyms
    PIM Protein, Pim-1 Protein, PIM1 Protein, pim Protein, pim-1 Protein, pim3 Protein, Pim-1 proto-oncogene, serine/threonine kinase Protein, proviral integration site 1 Protein, Pim-1 proto-oncogene, serine/threonine kinase L homeolog Protein, PIM1 Protein, Pim1 Protein, pim1 Protein, pim1.L Protein
    Background
    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].
    Molecular Weight
    35.5 kDa
    NCBI Accession
    NP_002639
    Pathways
    Glycosaminoglycan Metabolic Process
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